Accelerated Protein Research
Orbion is a predictive platform that transforms protein understanding, design, and validation into a precise science — starting with structure determination.
Accelerated Protein Research
Orbion is a predictive platform that transforms protein understanding, design, and validation into a precise science — starting with structure determination.
Accelerated Protein Research
Orbion is a predictive platform that transforms protein understanding, design, and validation into a precise science — starting with structure determination.
Protein research is a bumpy road.
Advances in structural biology, like AlphaFold and Cryo-EM, are revolutionizing how we study proteins. Yet, there are significant obstacles: unsuccessful purification attempts, difficulties around stabilizing proteins, and missing out on complex macromolecules.
The Purification Puzzle
Predicting protein–protein interactions is tricky. A single miscalculation can derail purification, wasting time and materials.
Protein Instability
Unstable proteins hamper the research. Pinpointing conditions and mutations that lock in their shape is essential to progress.
Overlooking Targets
Complex structures often get bypassed. In the rush for "low hanging fruits", we miss out on potentially game-changing discoveries.
Protein research is a bumpy road.
Advances in structural biology, like AlphaFold and Cryo-EM, are revolutionizing how we study proteins. Yet, there are significant obstacles: unsuccessful purification attempts, difficulties around stabilizing proteins, and missing out on complex macromolecules.
The Purification Puzzle
Predicting protein–protein interactions is tricky. A single miscalculation can derail purification, wasting time and materials.
Protein Instability
Unstable proteins hamper the research. Pinpointing conditions and mutations that lock in their shape is essential to progress.
Overlooking Targets
Complex structures often get bypassed. In the rush for "low hanging fruits", we miss out on potentially game-changing discoveries.
Protein research is a bumpy road.
Advances in structural biology, like AlphaFold and Cryo-EM, are revolutionizing how we study proteins. Yet, there are significant obstacles: unsuccessful purification attempts, difficulties around stabilizing proteins, and missing out on complex macromolecules.
The Purification Puzzle
Predicting protein–protein interactions is tricky. A single miscalculation can derail purification, wasting time and materials.
Protein Instability
Unstable proteins hamper the research. Pinpointing conditions and mutations that lock in their shape is essential to progress.
Overlooking Targets
Complex structures often get bypassed. In the rush for "low hanging fruits", we miss out on potentially game-changing discoveries.
Introducing Orbion
Orbion tackles the challenges of protein research through its predictive platform. By cutting both time and costs, Orbion makes it easier to work on difficult proteins while also supporting the protein design process.
Purification Guidelines
Gain insights into protein–protein interactions and simulate them effectively. Determine the best experimental methods to extract specific proteins from a mixture.
Deeper Protein Understanding
Uncover post-translational modifications, functional sites, and essential protein characteristics for a more accurate, comprehensive view.
Successful 3D Structures
Assess protein stability, predict mutations, and find optimal conditions for advanced techniques such as Cryo-EM and X-ray crystallography.
This leads to reduced research time and costs, possibility to work on challenging proteins, better and higher-resolution protein structures, and, happier scientists.
Introducing Orbion
Orbion tackles the challenges of protein research through its predictive platform. By cutting both time and costs, Orbion makes it easier to work on difficult proteins while also supporting the protein design process.
Purification Guidelines
Gain insights into protein–protein interactions and simulate them effectively. Determine the best experimental methods to extract specific proteins from a mixture.
Deeper Protein Understanding
Uncover post-translational modifications, functional sites, and essential protein characteristics for a more accurate, comprehensive view.
Successful 3D Structures
Assess protein stability, predict mutations, and find optimal conditions for advanced techniques such as Cryo-EM and X-ray crystallography.
This leads to reduced research time and costs, possibility to work on challenging proteins, better and higher-resolution protein structures, and, happier scientists.
Introducing Orbion
Orbion tackles the challenges of protein research through its predictive platform. By cutting both time and costs, Orbion makes it easier to work on difficult proteins while also supporting the protein design process.
Purification Guidelines
Gain insights into protein–protein interactions and simulate them effectively. Determine the best experimental methods to extract specific proteins from a mixture.
Deeper Protein Understanding
Uncover post-translational modifications, functional sites, and essential protein characteristics for a more accurate, comprehensive view.
Successful 3D Structures
Assess protein stability, predict mutations, and find optimal conditions for advanced techniques such as Cryo-EM and X-ray crystallography.
This leads to reduced research time and costs, possibility to work on challenging proteins, better and higher-resolution protein structures, and, happier scientists.
FAQ
What is Orbion?
Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.
How can I use Orbion?
You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.
Which proteins can Orbion work with?
Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.
How does Orbion provide predictions?
Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.
Is there a free option for academical or public research?
Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.
FAQ
What is Orbion?
Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.
How can I use Orbion?
You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.
Which proteins can Orbion work with?
Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.
How does Orbion provide predictions?
Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.
Is there a free option for academical or public research?
Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.
FAQ
What is Orbion?
Orbion is an AI-driven platform that helps scientists stabilize, engineer, and purify proteins more efficiently. Orbion identifies the most promising ways to modify proteins (e.g., truncations, mutations) and pinpoints the optimal conditions for structure determination—whether by crystallography or cryo-EM.
How can I use Orbion?
You can upload your protein sequence and any available structural or functional information into the Orbion platform. Orbion will then analyze potential PTMs, functional sites, and instability hotspots, suggest stabilizing modifications, and recommend experimental conditions for purification and structure determination. Think of it as a virtual collaborator, offering insights to guide your lab experiments and streamline your R&D process.
Which proteins can Orbion work with?
Orbion is designed to handle a wide range of proteins, from small soluble enzymes to large multi-domain or membrane-bound complexes. Our models are especially effective for challenging or unstable proteins that are traditionally difficult to crystallize or resolve using cryo-EM.
How does Orbion provide predictions?
Orbion uses neural networks and other machine-learning approaches trained on extensive protein data. Orbion generates scientifically grounded predictions on where and how to modify a protein, as well as which conditions are most likely to yield high-quality structural data.
Is there a free option for academical or public research?
Yes! If you are a researcher in academia or a public institute, and want to use Orbion for your public research studies, you can access Orbion for free. Simply, sign up for our researcher program, and we'll provide you the access very soon.
See Orbion's models in action.
Curious how Orbion's proprietary models streamline and accelerate protein research? Book a demo, and let us showcase you how to harness Orbion's capabilities for your research.
See Orbion's models in action.
Curious how Orbion's proprietary models streamline and accelerate protein research? Book a demo, and let us showcase you how to harness Orbion's capabilities for your research.
See Orbion's models in action.
Curious how Orbion's proprietary models streamline and accelerate protein research? Book a demo, and let us showcase you how to harness Orbion's capabilities for your research.
Orbion GmbH © Copyright 2025
Orbion GmbH © Copyright 2025
Orbion GmbH © Copyright 2025